5-[(Z)-(5-fluoro-2-oxo-1H-indol-3-ylidene)methyl]-2,4-dimethyl-N-[1,1,2,2-tetradeuterio-2-(diethylamino)ethyl]-1H-pyrrole-3-carboxamide - Names and Identifiers
5-[(Z)-(5-fluoro-2-oxo-1H-indol-3-ylidene)methyl]-2,4-dimethyl-N-[1,1,2,2-tetradeuterio-2-(diethylamino)ethyl]-1H-pyrrole-3-carboxamide - Physico-chemical Properties
Molecular Formula | C22H27FN4O2
|
Molar Mass | 398.48 |
Storage Condition | 2-8℃ |
5-[(Z)-(5-fluoro-2-oxo-1H-indol-3-ylidene)methyl]-2,4-dimethyl-N-[1,1,2,2-tetradeuterio-2-(diethylamino)ethyl]-1H-pyrrole-3-carboxamide - Introduction
Sunitinib-d4, a four-deuterium-labeled Sunitinib, is a broad-spectrum tyrosine kinase inhibitor. The following is a description of the nature, use, preparation and safety information of the Sunitinib-d4:
Nature:
Sunitinib-d4 is a white or off-white solid with the chemical structure C22H12D4F3N5O2 and a molecular weight of 454.48. It has good solubility and can be dissolved in water. The chemical properties of this compound are similar to those of Sunitinib.
Use:
Sunitinib-d4 are commonly used in research and analysis. It can be used as the internal standard substance of mass spectrometer for quantitative analysis of Sunitinib content in samples. In addition, Sunitinib-d4 can also be used in pharmacokinetic studies and drug interaction studies.
Method:
The Sunitinib-d4 can be synthesized by a synthetic method. The specific preparation method may be to react with a deuterated compound, and treat a hydrogen atom at an appropriate position in the pre-synthesized Sunitinib with a deuterated reagent, thereby preparing a labeled compound Sunitinib-d4 containing deuterium.
Safety Information:
Sunitinib-d4 safety information is relatively limited because it is mainly used for research and analysis purposes, rather than widely used as a drug or chemical. When using the Sunitinib-d4, it is necessary to follow the safety procedures of the laboratory and prevent contact with eyes, skin and inhalation. If necessary, the storage conditions and validity period of the substance should be checked regularly to ensure safe use.
Last Update:2024-04-09 02:00:54